
Combine the spices in a small bowl and mix well. Set aside.
Heat the vegetable oil in a large pot or Dutch oven to medium-high heat. Season the brisket pieces with salt and pepper, then sear them 1-2 minutes per side to get a nice brown crust on them. Do this in batches, if needed. Remove the brisket and set on to a plate.
Add the onion and jalapeno peppers. Cook 5 minutes to soften.
Stir in the garlic and half of the chili spice mixture. Cook for 1 minute to let the spices bloom.
Add the beef stock and scrape up any browned bits from the bottom of the pan.
Add the reserved brisket, fire roasted tomatoes, chili beans, Worcestershire sauce, and hot sauce. Stir.
Bring to a boil, then reduce the heat, cover and simmer for 1.5 hours.
Stir in the remaining chili spice mix and simmer, uncovered, for 1 hour, or until the brisket is tender to your preference.
Serve into bowls and top with your favorite toppings.